Mucous Cell Types

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The Role of Atoh1 in Mucous Cell Metaplasia

A key issue in otitis media is mucous cell metaplasia which is responsible for mucous hypersecretion and persistence of the disease. However, little is known about the molecular mechanisms of mucous cell metaplasia in otitis media. Numerous studies of intestinal epithelial homeostasis have shown that Atonal homolog 1 (Atoh1), a basic helix-loop-helix (bHLH) transcription factor, is essential fo...

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Immunogenetic programs for viral induction of mucous cell metaplasia.

Mucous secretions are frequently implicated in the morbidity and mortality associated with respiratory illness and airway disease, but we still do not understand precisely how these secretions develop or how to control them. A likely possibility is that the increased mucus is a consequence of overproduction and subsequent secretion in the setting of mucous cell metaplasia. In that regard, airwa...

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Mucin Production and Mucous Cell Metaplasia in Otitis Media

Otitis media (OM) with mucoid effusion, characterized by mucous cell metaplasia/hyperplasia in the middle ear cleft and thick fluid accumulation in the middle ear cavity, is a subtype of OM which frequently leads to chronic OM in young children. Multiple factors are involved in the developmental process of OM with mucoid effusion, especially disorders of mucin production resulting from middle e...

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Mucous membrane plasmacytosis

Mucous membrane plasmacytosis is a rare, idiopathic condition consisting of a dense plasma-cell infiltrate of the mucous membranes. Zoon first described a plasma-cell infiltrate occurring on the glans penis and plasmacytosis involving other body orifices have been reported under a variety of different terms. White et al. simplified the terminology by suggesting all plasma-cell infiltrates of th...

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Helicobacter pylori and two ultrastructurally distinct layers of gastric mucous cell mucins in the surface mucous gel layer.

BACKGROUND AND AIMS Helicobacter pylori locate not only on the apical surface of surface mucous cells but also in the mucous gel layer covering the gastric mucosa. The present study was undertaken to observe the mucous gel layer itself and any H pylori in this layer at the electron microscopic level, and to determine whether H pylori proliferate in this layer. METHODS We examined resected hum...

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ژورنال

عنوان ژورنال: Okajimas Folia Anatomica Japonica

سال: 1986

ISSN: 0030-154X

DOI: 10.2535/ofaj1936.63.1_1